Ivan Ivanov

(Selected Papers 2001-2011)

IN REFEREED JOURNALS

Mironova, R., Niwa, T., Hayashi, H, Dimitrova, R. and Ivanov, I. Evidence for non-enzymatic glycosylation in Escherichia coli. Mol. Microbiol. 39(2001)1061-68.

Altobelli G., Nacheva G., Todorova K., Ivanov I., Karshikoff A. Role of the C-terminal chain in human interferon gamma stability: An electrostatic study. Proteins: Str., Func., Genet. 43 (2001) 125-133.                                                                                                     

Golshani, A., Xu, J.,  Kolev, V., AbouHaidar, M. and Ivanov, I. Inability of Agrobacterium tumefaciens ribosome to translate in vivo mRNAs containing non-Shine-Dalgarno translational initiators. Zeitschr. Naturforsh.  57c (2002) 307-312.

Boyanova, M., Tsanev, R. and Ivanov, I. A  modified  kynurenine  bioassay for  quantitative determination  of  human   interferon  gamma. Analyt. Biochem. 308 (2002) 178-181.  

Boycheva, S. and Ivanov, I. Missing codon pairs in the genome of Escherichia coli. Biotechnol. Biotechnol. Equipm. 16 (2002) 142-144.

Nacheva, G., Boyanova, M., Todorova, K., Kyurkchiev, S.  and Ivanov, I. Characterization of functional domains of human interferon gamma by specific monoclonal antibodies. Folia Biologica 48 (2002) 96-101.

Nacheva, G., Todorova, K., Boycheva, M., Berzal-Herranz, A., Karshikov, A. and Ivanov, I. Human interferon-gamma: Significance of the C-terminal flexible domain for its biological activity. Arch. Biochem. Biophys. 413 (2003) 91-98.  

Boycheva, S., Shkodrov, G. and Ivanov, I. Codon pairs in the genome of Escherichia coli. Bioinformatics 29 (2003) 987-998.                                                                                           

Kolev, V., Ivanov, I., Berzal-Herranz, A. and Ivanov, I. Non-Shine-Dalgarno initiators of translation selected from a combinatorial DNA library. J. Mol. Microbiol. Biotechnol. 5 (2003) 154-160.

Atanassova, A., Sugita, M., Sugiura, M., Pajpanova, T. and Ivanov, I. Molecular cloning, expression and characterization of three distinctive genes encoding methionine aminopeptidases in cyanobacterium Synechocystis sp., strainPCC6803. Arch. Microbiol. 180 (2003) 185-193.

Mironova, R., Niwa, T., Dimitrova, R., Boyanova, M. and Ivanov, I. Glycation and post-translational processing of human interferon-gamma expressed in Escherichia coli. J. Biol. Chem. 278 (2003) 51068-51074.  

Boycheva, S., Bachvarov, B., Berzal-Heranz, A. and Ivanov, I.G. Effect of 3’terminal codon pairs with different frequency of occurrence on the expression of cat gene in Escherichia coli. Curr. Microbiol. 48 (2004) 97-101.

Golshani, A., Xu, J., Pacal, M., Yang, X., Ganoza, M., Ivanov, I. and AbouHaidar, M. Computationally identified and experimentally proven strong ribosome binding sites in the Escherichia coli genome. Biochem. Biophys. Res. Comm 316 (2004) 978-983.

Stoynev, G., Srebreva, L. and Ivanov, I.G. Histone H1 as a reporter protein to investigate glycation in bacteria. Curr. Microbiol. 49 (2004) 423-427.

Dimitrova, R., Mironova, R. and Ivanov, I.G. Glycation of proteins in Escherichia coli: Interference of strain diversity and growth conditions with glycation. Compt. Rend. Bulg. Acad. Sci. 57 (2004) 71-75.

Ivanov, I.V. and Ivanov, I.G. Enhancing activity of the epsilon (e) sequence is independent of its binding to domain 17 in 16S rRNA. Compt. Rend. Bulg. Acad. Sci. 57 (2004) 89-92.

 Mironova, R., Niwa, T., Handzhiyski, Y., Sredovska, A., and Ivanov, I. Evidence for non-enzymatic glycosylation of Escherichia coli chromosomal DNA. Mol. Microbiol. 55 (2005)  1801-1811.

Tsoncheva, V., Todorova, K., Maximova, V. and Ivanov, I.G. Spontaneous transfection of mammalian cells with plasmid DNA. Z. Naturforsch. 60c (2005) 644-648.

Butland G, Krogan NJ, Xu J, Yang WH, Aoki H, Li JS, Krogan N, Menendez J, Cagney G, Kiani GC, Jessulat MG, Datta N, Ivanov I, Abouhaidar MG, Emili A, Greenblatt J, Ganoza MC, Golshani A. Investigating the in vivo activity of the DeaD protein using protein-protein interactions and the translational activity of structured chloramphenicol acetyltransferase mRNAs. J. Cell. Biochem. 100 (2006) 642-652.

Tsanev, R., Boyanova, M. and Ivanov, I. Fluorescent analysis of interferon-gamma. Biotech. Biotechnol. Equipm. 21 (2007) 215-219.

Boyanova, M,  Mironova, R., Niwa, T. and Ivanov, I. (2008) Post-translational processing of human interferon-gamma produced in Escherichia coli and approaches for its prevention.  In: NIH Frontiers in Research, Vol. 1, Chapter 40, pp. 365-373, Humana Press, Totowa, NJ.

Tsoncheva V.L., Todorova K.A., Ivanov I.G. and Maximova V.A. Influence of Interferons on the Repair of UV-Damaged DNA. Z. Naturforsch. 63c (2008) 303-307.

Stoynev, G., Srebreva, L., Gugova, R., Golovinski, E. and Ivanov I. Inhibitory effect of some acetyl esters and acetamides on glycation of the histone H1. Z. Naturforsch. 63c (2008) 526-532.

Mironova, R., Sredovska, A., Ivanov, I. and Niwa, T. Maillard reaction products in the Escherichia coli derived therapeutic protein interferon Alfacon-1. Ann. N.Y. Acad. Sci. 1126 (2008) 181-184.

Bachvarov, B., Kirilov, K. and Ivanov, I. Codon usage in prokaryotes. Biotech. Biotechnol. Equipm. 22 (2008) 669-682.

Boyanova, M,  Mironova, R., Niwa, T. and Ivanov, I. (2008) Post-translational processing of human interferon-gamma produced in Escherichia coli and approaches for its prevention.  In: NIH Frontiers in Research, Vol. 1, Chapter 40, pp. 365-373, Humana Press, Totowa, NJ.

Petrov, S., Nacheva, G. and Ivanov, I. Purification and refolding of recombinant human interferon-gamma in urea-ammonium chloride solution. Protein Express. & Purificat. 73 (2010) 70-73.

Bagis, H., Aktoprakligil, D.,  Gunes, C., Arat, S., Akkos, T.,  Cetinkaya, G.,  Kankavi, O., Taskin, A., Arslan, K., Dundar, M.,  Tsoncheva, V. and Ivanov, I.G.  Expression of biologically active human interferon-gamma in the milk of transgenic mice under the control of the murine whey acidic protein gene promoter. Biochem Genet 1 (2010) DOI 10.1007/s10528-010-9403-7; ISSN 0006-2928.

Popov, M., Petrov, S., Nacheva, G., Ivanov, I., Reichl, U. Effects of a recombinant gene expression on ColE1-like plasmid segregation in Escherichia coli. BMC Biotechnology 11 (2011) 18-30.

Bozhinov A, Handzhiyski Y, Genov K, Daskalovska V, Niwa T, Ivanov I, Mironova R. Advanced glycation end products contribute to the immunogenicity of IFN-γ pharmaceuticals. J Allergy Clin Immun., 2011, doi: 10.1016/j.jaci.2011.10.035, ISSN 0091-6749.

Maximova V., Kirilov K., Markov S., Ivanov I. Comparative genomic studies of influenza A viruses performed on BlueGeneP supercomputer: Part 1. Conservative nucleotide sequences in influenza A virus genomes revealed by multiple sequence alignment. Bitechnol. & Biotechnol.Eq.  25 (2011) 2672-2678. ISSN 1310-2818.

Hinkov I, Diankov S, Karsheva M, Lasheva V, Ivanov I, Handzhiyski Y. Synthèse de nanoparticules d’argent par voie micro-onde et leur intégration dans des feuilles de cellulose pour des applications agroalimentaires. Revue de Génie Industriel, ISSN 1313-8871 (2011; in press).

MONOGRAPHS

Tsanev, R. and Ivanov, I. (2001) Immune Interferon: Properties and Clinical Applications. CRC Press, Bocka Raton, USA.

CHAPTERS IN BOOKS

Boyanova, M,  Mironova, R., Niwa, T. and Ivanov, I. (2008) Post-translational processing of human interferon-gamma produced in Escherichia coli and approaches for its prevention.  In: NIH Frontiers in Research, Vol. 1, Chapter 40, pp. 365-373, Humana Press, Totowa, NJ.

Bachvarov, B.I., Kirilov, K.T. and Ivanov, I. Codon and codon pairs usage in bacteria. In: Bacterial DNA, Chapter 1 (Knudsen, W.D. and Bruns, S.S., eds.), Nova Science Publishers, NY, USA (2010) pp. 3-49.

Mironova, R., Handzhiyski, Y., Niwa, T., Berzal-Heranz, A., Datsenko, K.,   Wanner, B. and Ivanov, I.G.  Maillard Reaction and Spontaneous Mutagenesis in Escherichia coli. In: Bacterial DNA, Chapter 2 (Knudsen, W.D. and Bruns, S.S., eds.), Nova Science Publishers, NY, USA (2010) pp. 51-89.

Mironova R, Handzhiyski Y. Niwa T, Berzal-Herranz A, Datsenko KA, Wanner BL, Ivanov I. Maillard Reaction and Spontaneous Mutagenesis in Escherichia coli. Chapter in: Encyclopedia of DNA Research (3 Volume Set), Eds: Samuel J. Duncan and Patricia H. Wiley, Nova Science Publishers, Inc., NY, USA. (in press) ISBN 978-1-61324-305-3.

Bachvarov, B., Kirilov, K. and Ivanov, I. Codon Usage and Gene Expression in Bacteria. In: Encyclopedia of DNA Research, Chapter 1 (Eds: Samuel J. Duncan and Patricia H. Wiley), Nova Science Publishers, Inc. NY, USA (in press) ISBN 978-1-61324-305-3.

PATENTS

Ivanov, I.G., Ivanov, V. P., Ivanova, V. S., Marekov, L. N., Vassileva, R. A., Sarafova, A. A., Tsanev, R. G. Method for producing of recombinant human cysteinless gamma-interferon free of methionine at N-terminal. EP 0 446 582 B1; C12N 15/23 (Date of publication: 04.01.1995; Appl. No 91100777.1; Date of filing: 22.01.91).

Ivanov, I., Tsanev, R., Nacheva, G., Grigoleit, H. and Gunther, R. Inhibitors of endogenous human interferon-gamma. International Patent WO2006/099701 A1; (Priority Date: 21.03.2005; Appl. No PCT/BG 05 796 484.3) Publication Date: 14.11.2011.

Ivanov, I., Nacheva, G., Petrov, S. and Grigoleit, H. Suppressors of the endogenous interferon-gamma. International Patent Appl. № РСТ/BG2008/000025.

Ivanov, I., Tsanev, R., Nacheva, G., Grigoleit, H. and Gunther, R. Inhibitors of endogenous interferon-gamma. US Patent 71973 133 82; Publication Date: 05.07.2011.