Name: Apostolova, Margarita D.
Date of birth: November  03, 1966
Nationality: Bulgarian
Languages:

English, Russian

Business address:

Institute of Molecular Biology
Bulgarian Academy of Sciences
Acad. G. Bontchev STR., bl 21
Sofia 1113

Phone: +3592-979-3684
Fax: +3592-728050
E-mail: margo@obzor.bio21.bas.bg
Present position:  Head of Medical and Biological Research Lab, Institute of Molecular Biology, Bulgarian Academy of Sciences
Education:

1984- National School of Mathematics and Natural Sciences, Sofia

1989- MSc. In Analytical and Inorganic Chemistry, Department of Analytical Chemistry, Sofia University, Bulgaria. "Synthesis and Characterization of new ligands for determination of microelements (Zn, Cu, Co, Pb, Cd)”

Scientific degrees: 1993– Ph.D. In Biology, Department of Biochemistry, Sofia University, Bulgaria. “Apometallothioneins and its metal complexes in relation to the arterial hypertension”.
Positions held:

2003 Head of Medical and Biological Research Lab, Bulgarian Academy of Sciences, Sofia, Bulgaria

1996-1998 Assistant Professor, Department of Chemistry and Biochemistry, Medical Academy, Sofia, Bulgaria

1993-1994 Research associate, Institute of Molecular Biology, Bulgarian Academy of Sciences, Sofia, Bulgaria

1993 Research associate, Institute of Molecular Biology, Bulgarian Academy of Sciences, Sofia, Bulgaria

Post-doctoral training:

2002-2003 In Molecular and Cellular Toxicology - Department of Lab Medicine and Pathobiology, University of Toronto.

2001-2002 Marie Curie Training Fellowship, In Proteomics – Protection by Zn and metallothionein against pathogenic mechanisms in atherogenesis - Department of Cellular Integrity, Rowett Research Institute, Aberdeen, Scotland.

2000-2001 In Molecular Biology and Pharmacology - E2F factors in cell growth and differentiation- Department of Pharmacology and Toxicology, University of Western Ontario, London, Canada.

1997-2000 In Metal Toxicology - Metalloprotein synthesis; expression in tumour cells, cell proliferation and differentiation; metals and apoptosis- Department of Pathology, University of Western Ontario, London, Canada.

1994-1996 In Environmental Health - Environmental Health Sciences Division, National Institute for Environmental Studies, Tsukuba, Japan.

Teaching activities:  

1996-1997- Assistant professor with full course lectures and lab practice for students in medicine, pharmacology and dentistry. For the general course in Biochemistry - Department of Chemistry and Biochemistry, Medical Academy, Sofia, Bulgaria

1991-1992 TA, Bioinorganic chemistry- Department of Analytical Chemistry, Sofia University, Bulgaria.

Research scope:  The role of Zn, Cu and biologically active polypeptides in the regulation of atherosclerosis and angiogenesis
Normal and abnormal signal transduction in human vascular disease
The impact of nanoparticles on human health and the environment
Research activity (publications): Peer reviewed research papers: 29
Impact factor: >59
Citations: >150
 
Awards received:

1999 First place in Metal Specialty Section of the Society of Toxicology (1999 Student Research Award, Postdoctoral), New Orleans, USA

Membership:

Member of Bulgarian League of Hypertension, since 1993

Member of Balkan Medical Union, since 1993

 


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